Amino acid composition of crystalline botulinum toxin, type A
نویسندگان
چکیده
منابع مشابه
The elemental and amino acid composition of crystalline Clostridium botulinum type A toxin.
The isolation of Clostridium botulinurn type A toxin in crystalline form (1, 2) has led to an interest in its chemical composition. An apparently complete analysis of the pure crystalline toxin is presented in this paper. Preliminary studies have indicated that the toxin is a protein with an isoelectric point of pH 5.6, possessing the properties of a globulin (l-3). It is free from carbohydrate...
متن کاملPhysicochemical Properties of Crystalline Clostridium Botulinum Type a Toxin*
Interest in the chemical nature and mode of action of bacterial toxins has been renewed by the simultaneously announced crystallization of botulinal (1) and tetanal toxins (2) and the recent purification of several toxoids (3-5). Of these, crystalline Clostridium botulinurn type A toxin alone has been submitted to an apparently complete elementary and amino acid analysis (6), as well as to prel...
متن کاملPhysiocochemical properties of crystalline Clostridium botulinum type A toxin.
Interest in the chemical nature and mode of action of bacterial toxins has been renewed by the simultaneously announced crystallization of botulinal (1) and tetanal toxins (2) and the recent purification of several toxoids (3-5). Of these, crystalline Clostridium botulinurn type A toxin alone has been submitted to an apparently complete elementary and amino acid analysis (6), as well as to prel...
متن کاملThe Amino Acid Composition of Crystalline Pepsin
The amino acid composition of twice recrystallized pepsin (Worthington Biochemical Corporation) has been determined chromatographically on columns of Amberlite IR 120 resin. The results of the analyses obtained on four different preparations indicate a close agreement in their amino acid composition. Pepsin is unique in that it has a great predominance of acidic amino acids over basic ones. Mor...
متن کاملMolecular weight of type a botulinum toxin.
Clostridium botulinum type A does not produce a 12,000 molecular weight toxin. The reported isolation of such a material by Gerwing et al. could not be confirmed.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1967
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.94.1.277-278.1967